Showing posts with label Medical Research. Show all posts
Showing posts with label Medical Research. Show all posts

Thursday, July 22, 2010

HEALTH NEWS

Don't let the phoney melanoma scare keep you out of the sun
There are many good reasons why we won't – and shouldn't – give up our tan

Sam Shuster The Guardian, Wednesday 21 July 2010

Kira Cochrane asks "why can't we give up the tan?" (Going for the burn, G2, 7 July). The answer is simple: we are not convinced that the alleged harm outweighs the obvious benefits, and we dislike the bullying, fear-mongering campaign against sun exposure.


Skin cancer statistics are used to scare, not educate. Almost all of the 84,000 skin "cancers" that appear each year are in fact benign: they don't spread or kill; their cancerous name is a historical misnomer. Of course, sun exposure increases facial wrinkling, as does smoking, but the black ace in the fear game is melanoma, because the real thing is vicious.


As the article tells us, Cancer Research UK say the incidence of malignant melanoma has "quadrupled in Britain in the last 30 years". But if this were so we would have seen coffin-loads of consequences by now. We haven't, and in a recently published large UK study (British Journal of Dermatology, 2009), I and my colleagues showed that the reason mortality has not increased with incidence is that the tumours reported are actually benign; they are not true malignant melanomas. Our explanation of the phoney melanoma epidemic is "diagnostic drift which classifies benign lesions as … melanoma", a misdiagnosis "driven by defensive medicine, an unsurprising response to its commercialisation".


The recategorisation by the International Agency for Research on Cancer that Cochrane quotes, which gives sunbeds "the same high risk … as cigarettes and asbestos", is absurd. The field is an unreliable mess of conflicting conclusions, and the claim of a special risk for younger people, which the article repeats, is now denied. But critically, since we now know incidence is invalidated by classifying benign disease as malignant, until diagnosis is improved only studies of melanoma mortality are acceptable; and the few that have been done show that melanoma mortality actually decreases after UV exposure!


The poor relationship of melanoma to cumulative UV dose had solarphobics running for cover in the idea the article quotes, that a one-off sunburn "could develop into a melanoma". But that doesn't happen: unlike the benign tumours that really are caused by UV, melanomas do not predominate in sun-exposed skin. There are commonsense reasons to avoid sunburn, and for use of sunscreens – but not, as Cochrane implies, to prevent melanoma, for which they have been shown to be ineffective.


Cochrane wonders why "we still associate tanned skin with good health", but there are many good reasons. Although the medical uses that gained Niels Ryberg Finsen a Nobel prize have long past, there are newer uses in photo-chemotherapy, dermatology and psychiatry.


Self-image is measurably increased by a tan, and we will learn much from understanding the mechanism of this wellbeing. UV initiates the synthesis of vitamin D, essential for our bones, and sunscreen promotion has led to problems. It also has a profound effect on our immune function. Strangely, the bastard science of descriptive epidemiology that masterminded the melanoma myth now claims that UV lowers the incidence of many internal cancers and melanoma, thereby outweighing any harmful effects.


Plants and animals owe their existence to the sun, and it is hardly surprising that we've learned to adapt and use it. That's why we can't give up our tan, and more importantly why we shouldn't try.

Thursday, February 18, 2010

HEALTH NEWS: MORE ON 'BIG PHARMA' SCAMS

Big Pharma researcher admits to faking dozens of research studies for Pfizer, Merck
Thursday, February 18, 2010
by Mike Adams, the Health Ranger
Editor of NaturalNews.com


"It's being called the largest research fraud in medical history. Dr. Scott Reuben, a former member of Pfizer's speakers' bureau, has agreed to plead guilty to faking dozens of research studies that were published in medical journals.

Now being reported across the mainstream media is the fact that Dr. Reuben accepted a $75,000 grant from Pfizer to study Celebrex in 2005. His research, which was published in a medical journal, has since been quoted by hundreds of other doctors and researchers as "proof" that Celebrex helped reduce pain during post-surgical recovery. There's only one problem with all this: No patients were ever enrolled in the study!

Dr. Scott Reuben, it turns out, faked the entire study and got it published anyway.

It wasn't the first study faked by Dr. Reuben: He also faked study data on Bextra and Vioxx drugs, reports the Wall Street Journal.

As a result of Dr. Reuben's faked studies, the peer-reviewed medical journal Anesthesia & Analgesia was forced to retract 10 "scientific" papers authored by Reuben. The Day of London reports that 21 articles written by Dr. Reuben that appear in medical journals have apparently been fabricated, too, and must be retracted.

After being caught fabricating research for Big Pharma, Dr. Reuben has reportedly signed a plea agreement that will require him to return $420,000 that he received from drug companies. He also faces up to a 10-year prison sentence and a $250,000 fine.

He was also fired from his job at the Baystate Medical Center in Springfield, Mass. after an internal audit there found that Dr. Reuben had been faking research data for 13 years. (
http://www.theday.com/article/20100...)

Business as usual in Big Pharma

What's notable about this story is not the fact that a medical researcher faked clinical trials for the pharmaceutical industry. It's not the fact that so-called "scientific" medical journals published his fabricated studies. It's not even the fact that the drug companies paid this quack close to half a million dollars while he kept on pumping out fabricated research.

The real story here is that this is business as usual in the pharmaceutical industry.

Dr. Reuben's actions really aren't that extraordinary. Drug companies bribe researchers and doctors as a routine matter. Medical journals routinely publish false, fraudulent studies. FDA panel members regularly rely on falsified research in making their drug approval decisions, and the mainstream media regularly quotes falsified research in reporting the news.

Fraudulent research, in other words, is widespread in modern medicine. The pharmaceutical industry couldn't operate without it, actually. It is falsified research that gives the industry its best marketing claims and strongest FDA approvals. Quacks like Dr Scott Reuben are an important part of the pharmaceutical profit machine because without falsified research, bribery and corruption, the industry would have very little research at all.

Pay special attention to the fact that the Anesthesia & Analgesia medical journal gladly published Dr. Reuben's faked studies even though this journal claims to be a "scientific" medical journal based on peer review. Funny, isn't it, how such a scientific medical journal gladly publishes fraudulent research with data that was simply invented by the study author. Perhaps these medical journals should be moved out of the non-fiction section of university libraries and placed under science fiction.

Remember, too, that all the proponents of pharmaceuticals, vaccines and mammograms ignorantly claim that their conventional medicine is all based on "good science." It's all scientific and trustworthy, they claim, while accusing alternative medicine of being "woo woo" wishful thinking and non-scientific hype. Perhaps they should have a quick look in the mirror and realize it is their own system of quack medicine that's based largely on fraudulent research, bribery and corruption.

You just have to laugh, actually, when you hear pushers of vaccines and pharmaceuticals claim their medicine is "scientific" while natural medicine is "unproven." Sure it's scientific -- about as scientific as the storyline in a Scooby Doo cartoon, or as credible as the medical license of a six-year-old kid who just received a "let's play doctor" gift set for Christmas. Many pharmaceutical researchers would have better careers as writers of fiction novels rather than scientific papers.

For all those people who ignorantly claim that modern pharmaceutical science is based on "scientific evidence," just give them these three words: Doctor Scott Reuben.

Drug companies support fraudulent research


Don't forget that the drug companies openly supported Dr. Scott Reuben's research. They paid him, in fact, to keep on fabricating studies.
The drug companies claim to be innocent in all this, but behind the scenes they had to have known what was going on. Dr. Reuben's research was just too consistently favorable to drug company interests to be scientifically legitimate. If a drug company wanted to "prove" that their drug was good for some new application, all they had to do was ask Dr. Reuben to come up with the research (wink wink). "Here's another fifty thousand dollars to study whether our drug is good for post-surgical pain (wink)."

And before long, Dr. Reuben would magically materialize a brand new study that just happened to "prove" exactly what the sponsoring drug company wanted to prove. Advocates of western medicine claim they don't believe in magic, but when it comes to clinical trials, they actually do: All the results they wish to see just magically appear as long as the right researcher gets paid to materialize the results out of thin air, much like waving a magician's wand and chanting, "Abra cadabra... let there be RESEARCH DATA!"

Shazam! The research data materializes just like that. It all gets written up into a "scientific" paper that also magically gets published in medical journals that fail to ask a single question that might exposed the research fraud.

I guess these people believe in magic after all, huh? Where science is lacking, a little "research magic" conveniently fills the void.

The whole system makes a mockery of real science. It is a system operated by criminals who fabricate whatever "scientific evidence" they need in order to get published in medical journals and win FDA approval for drugs that they fully realize are killing people.

What is "Evidence-Based Medicine?"


The fact that a researcher like Dr. Reuben could so successfully fabricate fraudulent study data, then get it published in peer-reviewed science journals, and get away with it for 13 years sheds all kinds of new light on what's really behind "evidence-based medicine."

The recipe for evidence-based medicine is quite simple: Fabricate the evidence! Get it published in any mainstream medical journal. Then you can quote the fabricated evidence as "fact!"

When pushers of pharmaceuticals and vaccines resort to quoting "evidence-based medicine" as their defense, keep in mind that much of their so-called evidence has been entirely fabricated. When they claim their branch of toxic chemical medicine is based on "real science," what they really mean is that it's based on fraudulent science but they've all secretly agreed to call it "real science." When they claim to have "scientific facts" supporting their position, what they really mean is that those "facts" were fabricated by criminal researchers being paid bribes by the drug companies.

"Evidence-based medicine," it turns out, hardly exists anymore. And even if it does, how do you know which studies are real vs. which ones were fabricated? If a trusted, well-paid researcher can get his falsified papers published for 13 years in top-notch science journals -- without getting caught by his peers -- then what does that say about the credibility of the entire peer-review science paper publishing process?

Here's what it says: "Scientific medicine" is a total fraud.

And this fraud isn't limited to Dr Scott Reuben, either. Remember: he engaged in routine research fraud for 13 years before being caught. There are probably thousands of other scientists engaged in similar research fraud right now who haven't yet been caught in the act. Their fraudulent research papers have no doubt already been published in "scientific" medical journals. They've been quoted in the popular press. They've been relied on by FDA decision makers to approve drugs as "safe and effective" for widespread use.

And yet underneath all this, there's nothing more than fraud and quackery. Sure, there may be some legitimate studies mixed in with all the fraud, but how can we tell the difference?

How are we to trust this system that claims to have a monopoly on scientific truth but in reality is a front for outright scientific fraud?

Keep up the great work, Dr Reuben


Thank you, Dr Scott Reuben, for showing us the truth about the pharmaceutical industry, the research quackery, the laughable "scientific" journals and the bribery and corruption that characterizes the pharmaceutical industry today. You have done more to shed light on the true nature of the drug industry than a thousand articles on NaturalNews.com ever could.

Keep up the good work. After paying your fine and serving a little jail time, I'm sure your services will be in high demand at all the top drug companies that need yet more "scientific" studies to be fabricated and submitted to the medical journals.

You may be a dishonest, disgusting human being to most of the world, but you're a huge asset to the pharmaceutical industry and they need you back! There are more studies that need to be fabricated soon; more false papers that need to be published and more dangerous drugs that need to receive FDA approval. Hurry!

Because if there's one place that extreme dishonesty is richly rewarded, it's in the pharmaceutical industry, where poisons are approved as medicines and fiction is published as the truth."

Sources for this story include:
http://www.nbcconnecticut.com/news/...

http://blogs.wsj.com/health/2010/01...

http://www.medpagetoday.com/PublicH...

http://www.theday.com/article/20100...

Sunday, January 24, 2010

MUST READ: THE FLU/VACCINE SCAM

Pulling back the curtain
on swine flu.. From the "DAILY DOSE"

"Looks like the swine flu "crisis" has finally unraveled -- just as I've warned right from the start. A leading European health official is now pushing for an investigation into the so-called pandemic -- and the desperate push to line Big Pharma pockets at your expense.

Dr. Wolfgang Wodarg, health chief at the Council of Europe, put it best when he told the European press, "We have had a mild flu -- and a false pandemic." His resolution calling for the investigation passed the Council, setting the stage for an emergency debate. It seems they've finally realized that the real emergency isn't the flu -- it's the lies we've been told about it, and the dangerous vaccines forced on millions based on those filthy falsehoods.

The good doctor -- turns out there are still a few of us left -- is even calling the non-pandemic "one of the greatest medical scandals of the century." We're only a decade into this century -- we've still got 90 years to see what else Big Pharma has up its sleeve! But already, this one's been a doozy. It'll be hard to top Vioxx in terms of death and destruction... but as far as swindles go, swine flu takes the prize. Around the world, supposedly concerned and impartial health "experts" all predicted terrifying (and ultimately nonexistent) consequences from the swine flu... and many of them just so happened to have financial ties to Big Pharma.

Maybe that's why the World Health Organization was so quick to change its definition of "pandemic" to make swine flu fit the bill. These same experts are now warning of a swine flu "third wave" and urging more people to submit to the needle. Listen closely and you might hear them laughing as they count their money. Give it a rest already, guys. This con job's over."

William Campbell Douglass II, M.D.

More:
http://www.naturalnews.com:80/027984_swine_flu_vaccines.html

http://www.youtube.com/watch?v=l1K74Tnrrok

http://www.wanttoknow.info/healthmediaarticles


http://www.wanttoknow.info/a-swine-flu-fear-mongering

Friday, August 07, 2009

HEALTH NEWS

Caffeine May Prevent and Help Reverse Alzheimer's

(NaturalNews) There is probably no more dreaded and feared disease than memory-destroying and life-robbing Alzheimer's. According to the National Institute on Aging (NIA), as many as 2.4 to 4.5 million Americans are currently living with Alzheimer's Disease (AD) and, as Baby Boomers age, those numbers are expected to soar. Unfortunately, despite millions spent on research and the development of drugs to delay or help symptoms, the bottom line is nothing works to truly prevent, stop or heal the disease. At least, nothing from Big Pharma. The National Institutes of Health's NIA web site does list some natural strategies -- a nutritious diet, exercise, social engagement, and mentally stimulating pursuits -- which may prevent or delay AD. But now there's new and stunning research that strongly suggests a substance found in nature offers another a way to fight Alzheimer's and maybe even reverse its effects: caffeine.


In experiments with lab mice especially bred to develop symptoms of Alzheimer's disease, University of South Florida (USF) researchers at the Florida Alzheimer's Disease Research Center ADRC gave the aged animals the equivalent of the caffeine in five cups of coffee a day. The results? Their severe memory impairment was reversed.This study, along with other AD research by the same group of scientists, was just published in the Journal of Alzheimer's Disease. Both studies show that caffeine significantly decreased abnormal levels of beta amyloid (the protein linked to AD) in both the brains and blood of lab rodents who had symptoms of Alzheimer's. This research follows on the heels of previous ADRC research that found caffeine given to this same strain of mice when they were young prevented memory problems from developing -- even though the animals were bred to develop Alzheimer's symptoms as they grew old.

"The new findings provide evidence that caffeine could be a viable 'treatment' for established Alzheimer's disease, and not simply a protective strategy," said lead author Gary Arendash, PhD, a USF neuroscientist with the Florida ADRC, in a statement to the media. "That's important because caffeine is a safe drug for most people, it easily enters the brain, and it appears to directly affect the disease process."Dr. Arendash and his research team began investigating caffeine's ability to possibly treat Alzheimer's after they read a Portuguese study conducted a few years ago that found people with Alzheimer's had consumed far less caffeine over the last 20 years than people who never came down with AD. There have also been several uncontrolled clinical studies that have noted moderate caffeine consumption seems to offer protection against memory decline during normal aging.

So the ADRC scientists decided to conduct highly controlled experiments using Alzheimer's afflicted mice in order to distinguish the effects caffeine might actually have on memory from other lifestyle factors such as diet and exercise.The Florida ADRC study used 55 of the genetically altered mice who develop memory problems identical to Alzheimer's disease as they become old. Behavior tests were conducted to confirm the mice were experiencing memory problems when they reached the age of 18 to 19 months, the equivalent of a human who's around 70. Then the scientists gave half the mice caffeine-laced water -- in all, they received the equivalent of five eight oz. cups of regular coffee a day. As a control, the other half of the mice in the study group received plain water.

After two months, the caffeinated mice could perform much better on tests designed to measure their memory and ability to think. Although the mice that drank plain water continued to show mental deterioration, the mice on caffeine not only had stopped losing their memories, their memories were identical to normal aged mice without dementia. Moreover, the caffeinated mice showed an approximate 50 percent reduction in beta amyloid, the substance linked to sticky lumps of plaques in the brain that are the key sign of Alzheimer's disease.More experiments by the same research team suggest that caffeine has the ability to restore memory by reducing the enzymes needed to produce beta amyloid. In fact, the Florida scientists think caffeine may suppress inflammatory changes in the brain that lead to the AD-associated increase of beta amyloid.

"These are some of the most promising Alzheimer's mouse experiments ever done showing that caffeine rapidly reduces beta amyloid protein in the blood, an effect that is mirrored in the brain, and this reduction is linked to cognitive benefit," Huntington Potter, PhD, director of the Florida ADRC and an investigator for the caffeine studies, said in the media statement. "Our goal is to obtain the funding needed to translate the therapeutic discoveries in mice into well-designed clinical trials." Based on their groundbreaking findings in mice, scientists at Florida ADRC and Byrd Alzheimer's Center at USF want to carry out human trials to see if caffeine can benefit people with mild cognitive impairment or early Alzheimer's disease. There's strong reason to think caffeine can fight AD. The researchers have already determined in preliminary studies that caffeine given to elderly non-demented humans quickly affects their blood levels of beta amyloid, just as it did in the Alzheimer's lab animals. If larger, well documented and controlled clinical studies do confirm caffeine can prevent and/or treat Alzheimer's in humans, as it does in mice, the ramifications will be nothing short of mind-boggling. According to the Alzheimer's Association, at least half of the US population 85 and older have or end up with AD and the disease and other dementias triple healthcare costs for Americans 65 and older, in addition to causing untold suffering .



Editor's note: NaturalNews is opposed to the use of animals in medical experiments that expose them to harm. We present these findings in protest of the way in which they were acquired. We are also opposed to the idea of using large volumes of caffeine as a "treatment" for Alzheimer's, especially given the adrenal depletion caused by ongoing caffeine consumption. The conclusions presented in this story are interesting, but in no way does NaturalNews condone the regular consumption of caffeine as a brain stimulant.

References :Caffeine Reverses Cognitive Impairment and Decreases Brain Amyloid-B Levels in Aged Alzheimer's Disease Mice; Gary W Arendash, Takashi Mori, Chuanhai Cao, Malgorzata Mamcarz, Melissa Runfeldt, Alexander Dickson, Kavon Rezai-Zadeh, Jun Tan, Bruce A Citron, Xiaoyang Lin, Valentina Echeverria, and Huntington Potter; Journal of Alzheimer's Disease, Volume 17:3 (July 2009).Caffeine Suppresses Amyloid-B Levels in Plasma and Brain of Alzheimer's Disease Transgenic Mice; Chuanhai Cao, John R Cirrito, Xiaoyang Lin, Lilly Wang, Deborah K Verges, Alexander Dickson, Malgorzata Mamcarz, Chi Zhang, Takashi Mori, Gary W Arendash, David M Holzman, and Huntington Potter; Journal of Alzheimer's Disease, Volume 17:3 (July 2009For more information :http://www.nia.nih.gov/Alzheimers/P...http://www.nia.nih.gov/Alzheimers



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